Hedgehog signaling is required for many aspects of development in vertebrates and invertebrates.Misregulation of the Hedgehog pathway causes developmental abnormalities and has been implicated in certain types of Goal Neck cancer.Large-scale genetic screens in zebrafish have identified a group of mutations, termed you-class mutations, that share co
Investigating the genetic architecture of eye colour in a Canadian cohort
Summary: Eye color is highly variable in populations with European ancestry, ranging from low to high quantities of HEPATO DR melanin in the iris.Polymorphisms in the HERC2/OCA2 locus have the largest effect on eye color in these populations, although other genomic regions also influence eye color.We performed genome-wide association studies of eye
Spreading of heterochromatin and karyotype differentiation in two Tropidacris Scudder, 1869 species (Orthoptera, Romaleidae)
Tropidacris Scudder, 1869 is a genus widely distributed throughout the Neotropical region where speciation was probably promoted by forest reduction during the glacial and interglacial periods.There are no cytogenetic studies of Tropidacris, and information allowing inference or confirmation of the evolutionary events involved in speciation within